Class I: Benefit >>> Risk
Conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective.
Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
Class IIa: Benefit >> Risk
Weight of evidence/opinion is in favor of usefulness/efficacy.
Class IIb: Benefit ≥ Risk
Usefulness/efficacy is less well established by evidence/opinion.
Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/effective and in some cases may be harmful.
Class III: No Benefit
Is not recommended, not indicated, should not be performed/ administered/ other. Is not useful/beneficial/effective.
Class III: Harm
Potentially harmful, causes harm, associated with excess morbidity/mortality. Should not be performed/administered/other.
Use the Level of Evidence designation to indicate the strength of the data associated with that recommendation.